Speciality Chemicals

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Remdesivir Intermediate 2-ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate CAS: 1911578-98-7 Purity: 98% Products Description Name 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate Synonyms Remdesivir-001 Molecular Structure Molecular Formula C21H27N2O7P Molecular Weight 495.38 CAS Registry Number 1911578-98-7 Basic Information Port: Beijing, China Production Capacity: 100000000kg Payment Terms: L/C, T/T CAS No.: 1911578-98-7 Formula: C21h27n2o7p Type: Pharmaceutical Intermediates Appearance: Powder Quality: Industrial Colour: White

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Ethyl trifluoroacetate can be used • To synthesize cyclopentenones or furans containing trifluoromethyl group from aromatic ynones. • In the selective trifluoroacetylation of anilines catalyzed by 4-dimethylaminopyridine. • As a starting material in the two-step electrosynthesis of trifluoroacetyltrimethylsilane (CF3COSiMe3). • In the preparation of trifluoromethyl ketones via trifluoroacetic ester/ketone metathesis with alkyl aryl ketones. • To synthesize o-fluorinated trifluoro acetophenones from substituted fluorobenzene

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Application:CAS: 5570-77-4, MF: C6H12ClN, MW: 133.6, Purity: ≥98% CAS Number:5570-77-4 Purity:≥98% Molecular Weight:133.6 Molecular Formula:C6H12ClN Physical State :Liquid Solubility :Soluble in water. Miscible in ethanol, and acetone. Storage :Store at room temperature Melting Point :160-165° C Boiling Point :162° C Density :1.04 g/mL Refractive Index :n20D 1.47 Physical State :Liquid Solubility :Soluble in water. Miscible in ethanol, and acetone. Storage :Store at room temperature Melting Point :160-165° C Boiling Point :162° C Density :1.04 g/mL Refractive Index :n20D 1.47

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Chemical Name: 2-aminopropanedinitrile CAS.NO:5181-05-5 Synonyms: 2-aminopropanedinitrile; Aminomalononitrile Molecular Formula: C3H3N3 Molecular Weight: 0 Packing: 1kg / 25kgs or as per customer requirement Storage: Store in a tightly closed container, cool and dry place Material Safety Information (Applicable for Hazard Chemicals) We provide one-stop services for the development, development and production of various organic chemicals as well as special compounds and pharmaceutical intermediates.Our company has won the trust of customers at home and abroad with competitive price, high quality products, quick response, high quality sales service, steady and honest style, and the concept of providing one-stop service for customers. and support.Provide high quality, regulatory compliance products and services to partners and customers.

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• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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Application • Reactant for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction • Reactant for chemoselective and regioselective preparation of benzoyl indoles • Reactant for preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM • Reactant for preparation of 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant • Reactant for preparation of vinylindoles by hydroarylation of alkynes using indium bromide catalyst • Reactant for gold catalyzed direct alkynylation using a benziodoxolone based hypervalent iodine reagent

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• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

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GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM The cells appear and grow normally at all concentrations of GS-441524 and fail to uptake the fluorescent dye CellTox Green at 24 h. The cytotoxic concentration-50% (CC50) is therefore>100 μM. The effective concentration-50% (EC50) of GS-441524 is calculated to be 0.78 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. All 10 treated cats have a rapid response to treatment and lymphocyte levels and rectal temperatures return to pre-infection levels and levels of the two asymptomatic cats. All ten of the once or twice treated cats have remained normal to date (more than eight months post infection). Injections cause a transient "stinging" reaction in some cats within 10 s of compound administration. Localized and transient pain is evidenced by unusual posturing, licking at the injection site and/or vocalizations that last for approximately 30-60 s after injection. Injection reactions are more pronounced in some animals relative to others and reactions are inconsistent from one injection to the next and decreas over time[1]. Remdesivi (IV injection) in NHP results in GS-441524 being present in serum at concentrations 1000-fold higher than Remdesivir throughout a 7-day treatment course. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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