Bull Pharmachem
Bull Pharmachem
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Oncology Medicine

Providing you the best range of mekinist trametinib 2 mg tablets, lonsurf trifluridine and tipiracil 15mg tablets, esbriet pirfenidone tablets, pirfenex pirfenidone tablets 200mg, caprelsa vandetanib 300 mg tablets and xpovio selinexor 80 mg tablets with effective & timely delivery.

Mekinist Trametinib 2 mg Tablets

Mekinist Trametinib 2 mg Tablets
  • Mekinist Trametinib 2 mg Tablets
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Packaging Size30 Tablets
BrandMekinist
CompositionTrametinib
ManufacturerNovartis
TreatmentSkin Cancer
FormTablet
Shelf life2 Years
Therapeutic UsesSkin Cancer

Mekinist (Trametinib 2mg) is a prescription medicine used: alone or in combination with a medicine called dabrafenib to treat a type of skin cancer called melanoma: that has spread to other parts of the body or cannot be removed by surgery, and that has a certain type of abnormal “BRAF” gene. in combination with dabrafenib, to help prevent melanoma that has a certain type of abnormal “BRAF” gene from coming back after the cancer has been removed by surgery. Mekinist should not be used to treat people who already have received a BRAF inhibitor for treatment of their melanoma, and it did not work or is no longer working. in combination with dabrafenib to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body, and that has a certain type of abnormal “BRAF” gene. in combination with dabrafenib to treat a type of thyroid cancer called anaplastic thyroid cancer (ATC) that has spread to other parts of the body and you have no satisfactory treatment options, and that has a certain type of abnormal “BRAF” gene What are the possible side effects of Mekinist? Mekinist may cause serious side effects, including: See “What is the most important information I should know about Mekinist?” bleeding problems. Mekinist can cause serious bleeding problems, especially in your brain or stomach, that can lead to death. Call your healthcare provider and get medical help right away if you have any signs of bleeding, including: headaches, dizziness, or feeling weak cough up blood or blood clots vomit blood or your vomit looks like “coffee grounds” red or black stools that look like tar inflammation of the intestines, or tears (perforation) of the stomach or intestines. Mekinist can cause inflammation of your intestines, or tears in the stomach or intestines that can lead to death. Tell your healthcare provider immediately if you have any of the following symptoms: bleeding. see “bleeding problems” above diarrhea (loose stools) or more bowel movements than usual stomach-area (abdomen) pain or tenderness fever nausea blood clots. Mekinist can cause blood clots in your arms or legs, which can travel to your lungs and can lead to death. Get medical help right away if you have the following symptoms: chest pain sudden shortness of breath or trouble breathing pain in your legs with or without swelling swelling in your arms or legs a cool pale arm or leg heart problems, including heart failure. Your healthcare provider should check your heart function before and during treatment with Mekinist. Call your healthcare provider right away if you have any of the following signs and symptoms of a heart problem: feeling like your heart is pounding or racing shortness of breath swelling of your ankles and feet feeling lightheaded eye problems. Mekinist can cause severe eye problems that might lead to blindness. Call your healthcare provider right away if you get these symptoms of eye problems: blurred vision, loss of vision, or other vision changes see color dots halo (seeing blurred outline around objects) eye pain, swelling, or redness lung or breathing problems. Mekinist can cause lung or breathing problems. Tell your healthcare provider if you have any new or worsening symptoms of lung or breathing problems, including: shortness of breath cough fever. Fever is common during treatment with Mekinist and dabrafenib, but it may also be serious. When taking Mekinist with dabrafenib, fever may happen more often or may be more severe. In some cases, chills or shaking chills, too much fluid loss (dehydration), low blood pressure, dizziness, or kidney problems may happen with the fever. Call your healthcare provider right away if you get a fever during treatment with Mekinist.
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  • Production Capacity: NA
  • Delivery Time: Immediate
  • Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.
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Lonsurf Trifluridine And Tipiracil 15mg Tablets

Lonsurf Trifluridine And Tipiracil 15mg Tablets
  • Lonsurf Trifluridine And Tipiracil 15mg Tablets
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ManufacturerTaiho Oncology Inc.
Packaging Size40 Tablets
Packaging TypeBottle
BrandLonsurf
CompositionTrifluridine and Tipiracil
Usage/ApplicationColorectal Cancer
FormTablets
Shelf Life2 Years

LONSURF (Trifluridine and Tipiracil 15mg)is a prescription medicine used to treat adults with colorectal cancer that has spread to other parts of the body and who have been previously treated or cannot receive certain chemotherapy medicines. a kind of stomach cancer called gastric cancer including cancer of the gastroesophageal junction that has spread to other parts of the body and who have been previously treated or cannot receive certain chemotherapy medications. It is not known if LONSURF is safe and effective in children IMPORTANT SAFETY INFORMATION LONSURF may cause serious side effects, including: Low blood counts. Low blood counts are common with LONSURF and can sometimes be severe and life-threatening. LONSURF can cause a decrease in your white blood cells, red blood cells, and platelets. Low white blood cells can make you more likely to get serious infections that could lead to death. Your healthcare provider should do blood tests before you receive LONSURF, at day 15 during treatment with LONSURF, and as needed to check your blood cell counts. Your healthcare provider may lower your dose of LONSURF or stop LONSURF if you have low white blood cell or platelet counts Tell your healthcare provider right away if you get any of the following signs and symptoms of infection during treatment with LONSURF: fever, chills, or body aches. Before taking LONSURF, tell your healthcare provider about all of your medical conditions, including if you: Have kidney or liver problems Are pregnant or plan to become pregnant. LONSURF can harm your unborn baby. Females who can become pregnant: Your healthcare provider will verify your pregnancy status before you start treatment with LONSURF. You should use effective birth control during and 6 months after the last dose of treatment with LONSURF. Tell your healthcare provider immediately if you become pregnant Males, while on treatment and for 3 months after your last dose of LONSURF, you should use a condom during sex with female partners who are able to become pregnant. Tell your healthcare provider right away if your partner becomes pregnant while you are taking LONSURF Are breast-feeding or plan to breast-feed. It is not known if LONSURF passes into your breast milk. Do not breast-feed during treatment with LONSURF and for 1 day after your last dose of LONSURF Tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. The most common side effects with LONSURF include tiredness (fatigue, weakness), nausea, decreased appetite, diarrhea, vomiting, abdominal pain, and fever. Tell your doctor if you have nausea, vomiting, or diarrhea that is severe or that does not go away. These are not all of the possible side effects of LONSURF. For more information, ask your healthcare provider. Call your doctor for medical advice about side effects.
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Esbriet Pirfenidone Tablets

Esbriet Pirfenidone Tablets
  • Esbriet Pirfenidone Tablets
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Packaging Size90 Tablets
Packaging TypeBottle
BrandEsbriet
CompositionPirfenidone
Manufactured ByGenentech
Strength801 Mg
TreatmentIdiopathic Pulmonary Fibrosis

Esbriet (Pirfenidone 801 Mg) is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF). It is not known if Esbriet is safe and effective in children. Select Important Safety Information Before you take Esbriet, tell your doctor about all of your medical conditions, including if you: have liver problems. have kidney problems. are a smoker. are pregnant or plan to become pregnant. It is not known if Esbriet will harm your unborn baby. are breastfeeding or plan to breastfeed. It is not known if Esbriet passes into your breast milk. You and your doctor should decide if you will take Esbriet or breastfeed. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. What should I avoid while taking Esbriet? Sunlight. Esbriet can make your skin sensitive to the sun and the light from sunlamps and tanning beds. You could get a severe sunburn. Use sunscreen (SPF 50) and wear a hat and clothes that cover your skin if you have to be in sunlight. Talk to your doctor if you get sunburn or a rash. Taking Esbriet with other medicines that can make your skin sensitive to the sun, the light from sunlamps and tanning beds. Smoking. Smoking may affect how well Esbriet works. What are the possible side effects of Esbriet? Esbriet may cause serious side effects, including: liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, or feeling tired. Your doctor will do blood tests to check how your liver is working during your treatment with Esbriet. sensitivity to sunlight (photosensitivity) and rash. See “What should I avoid while taking Esbriet?” stomach problems. Esbriet may cause stomach problems such as nausea, vomiting, diarrhea, indigestion, heartburn, and stomach pain. Tell your doctor right away if your stomach problems get worse or do not go away. Your doctor may need to change your dose of Esbriet. The most common side effects of Esbriet include feeling tired, insomnia, upper respiratory tract infections, sinusitis, headache, dizziness, decreased weight and decreased or loss of appetite. These are not all the possible side effects of Esbriet.
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Additional Information:

  • Production Capacity: NA
  • Delivery Time: Immediate
  • Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.
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Pirfenex Pirfenidone Tablets 200mg

Pirfenex Pirfenidone Tablets 200mg
  • Pirfenex Pirfenidone Tablets 200mg
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Packaging Size3 x 10 Tablets
Packaging TypeBox
BrandPirfenex
Active IngredientPirfenidone
Manufactured ByCipla Ltd
Shelf Life2 Years
Strength200 Mg
TreatmentIdiopathic Pulmonary Fibrosis
Storage25 Degree C (77 Degree F)

PIRFENEX (Pirfenidone 200 Mg) Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better. Pirfenex Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include insomnia, headache, and dizziness. To overcome dizziness, avoid driving or attention-seeking activity. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine. Before taking this medicine, let your doctor know if you have liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. It makes your skin sun-sensitive, wear protective clothing or apply sunscreen while in direct contact with the sun. Inform your doctor if you are pregnant or breastfeeding. 
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Caprelsa Vandetanib 300 mg Tablets

Caprelsa Vandetanib 300 mg Tablets
  • Caprelsa Vandetanib 300 mg Tablets
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Packaging Size30 Tablets
BrandCaprelsa
CompositionVandetanib
ManufacturerAstraZeneca
TreatmentThyroid Cancer
FormTablet
Shelf life2 Years

Caprelsa (Vandetanib 300 mg) is a prescription medicine used to treat medullary thyroid cancer that cannot be removed by surgery or that has spread to other parts of the body. It takes a long time to get rid of Caprelsa from your body and you may be at risk for side effects related to Caprelsa after you have stopped your treatment. It is not known if Caprelsa is safe and effective in children. What are the possible side effects of Caprelsa? Caprelsa may cause serious side effects, including: Serious skin reactions. Caprelsa can cause serious skin reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome, or other serious skin reactions that may affect any part of your body. These serious skin reactions may be life threatening and you may need to be treated in a hospital. Call your healthcare provider right away if you experience any of these symptoms. Skin rash or acne Dry skin Itching Blisters on your skin Blisters or sores in your mouth Peeling of your skin Fever Muscle or joint aches Redness or swelling of your face, hands, or soles of your feet Breathing problems (interstitial lung disease). Caprelsa may cause a breathing problem called interstitial lung disease that can lead to death. Tell your healthcare provider right away if you experience sudden or worsening shortness of breath or cough. Stroke. Strokes have been reported in some people who have taken Caprelsa and in some cases have caused death. Stop taking Caprelsa and call your healthcare provider right away if you have symptoms of a stroke which may include: numbness or weakness of the face, arm or leg, especially on one side of the body sudden confusion, trouble speaking or understanding sudden trouble seeing in one or both eyes sudden trouble walking, dizziness, loss of balance or coordination sudden, severe headache Bleeding. Bleeding can happen during your treatment with Caprelsa. Tell your healthcare provider right away if you have severe bleeding while you are taking Caprelsa. Heart failure. Caprelsa can cause heart failure that can lead to death. You may have to stop taking Caprelsa if you have heart failure. Heart failure may not be reversible after stopping Caprelsa. Your healthcare provider should monitor you for signs and symptoms of heart failure. Diarrhea. Diarrhea is often a symptom of medullary thyroid cancer. Caprelsa can also cause diarrhea or make diarrhea worse. Your healthcare provider should check your blood levels to monitor your electrolytes more frequently if you have diarrhea. Thyroid hormones. You can have changes in your thyroid hormone when taking Caprelsa. Your healthcare provider should monitor your thyroid hormone levels while taking Caprelsa. High blood pressure (hypertension). If you develop high blood pressure or your high blood pressure gets worse, your healthcare provider may lower your dose of Caprelsa or tell you to stop taking Caprelsa until your blood pressure is under control. Your healthcare provider may prescribe another medicine to control your high blood pressure. Reversible Posterior Leukoencephalopathy Syndrome (RPLS). A condition called reversible posterior leukoencephalopathy syndrome can happen while taking Caprelsa. Call your healthcare provider right away if you have: headaches seizures confusion changes in vision problems thinking The most common side effects of Caprelsa include: diarrhea rash acne nausea high blood pressure headache feeling tired loss of appetite upper respiratory tract infections stomach (abdominal) pain Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Caprelsa. For more information, ask your healthcare provider or pharmacist.
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Xpovio Selinexor 80 mg Tablets

Xpovio Selinexor 80 mg Tablets
  • Xpovio Selinexor 80 mg Tablets
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ManufacturerKaryopharm
BrandXpovio
Dose Strength80 Mg
CompositionSelinexor
Generic NameSelinexor
Dosage FormOral
Packaging TypeBox
Packaging Size16 Flim Coated Tablets
FormTablets
Shelf Life2 Years

XPOVIO (Selinexor) is a prescription medicine used: in combination with bortezomib and dexamethasone to treat adult patients with multiple myeloma who have received at least one prior therapy. It is not known if XPOVIO is safe and effective in children less than 18 years of age. Your healthcare provider will do blood tests before you start taking XPOVIO, and often during the first 3 months of treatment, and then as needed during treatment. XPOVIO can cause serious side effects, including: Low platelet counts. Low platelet counts are common with XPOVIO and can lead to bleeding, which can be severe and can sometimes cause death. Your healthcare provider may prescribe platelet transfusions or other treatments for your low platelet counts. Tell your healthcare provider right away if you have any bleeding or easy bruising during treatment with XPOVIO. Low white blood cell counts. Low white blood cell counts are common with XPOVIO and can sometimes be severe. You may have an increased risk of getting bacterial infections during treatment with XPOVIO. If needed, your healthcare provider may prescribe antibiotics if you have signs or symptoms of infection. Serious infections. Infections are common with XPOVIO and can be serious and can sometimes cause death. This includes upper or lower respiratory tract infections, such as pneumonia, and an infection throughout your body (sepsis). Tell your healthcare provider right away if you have any signs or symptoms of an infection such as cough, chills, or fever during treatment with XPOVIO. Neurologic side effects. XPOVIO can cause dizziness, fainting, decreased alertness, and changes in your mental status, including problems with thinking, seeing or hearing things that are not really there (hallucinations). These problems can sometimes be severe and life-threatening. Tell your healthcare provider right away if you get any of these symptoms. Do not drive or operate heavy or dangerous machinery until you know how XPOVIO affects you. Take precautions to prevent a fall. Nausea, vomiting, and/or diarrhea. Nausea, vomiting, and/or diarrhea can occur when you take XPOVIO and can sometimes be severe. You may be at risk for becoming dehydrated. Your healthcare provider may prescribe anti-nausea or anti-diarrhea medicines. Loss of appetite and weight loss. Loss of appetite and weight loss are common with XPOVIO. Tell your healthcare provider if you have a decrease or loss of appetite and if you are losing weight. Decreased sodium levels in your blood. Decreased sodium levels in your blood are common with XPOVIO. Your healthcare provider may talk with you about your diet and prescribe IV fluids or salt tablets. New or worsening cataract, cloudiness, or loss of transparency of the lens in the eye. New or worsening cataract are common with XPOVIO. If a cataract forms, your vision may decrease, and you may need eye surgery to remove the cataract and restore your vision. Tell your healthcare provider right away if you have symptoms of a cataract such as double vision, blurred vision, or sensitivity to light or glare. Common side effects of XPOVIO include: tiredness weakness low red blood cell count (anemia). Symptoms may include tiredness and shortness of breath constipation shortness of breath increased blood sugar changes in body salt and mineral levels in your blood changes in kidney and liver function blood tests These are not all of the possible side effects of XPOVIO.
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Additional Information:

  • Production Capacity: NA
  • Delivery Time: Immediate
  • Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.
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Relumina Relugolix 40mg Tablets

Relumina Relugolix 40mg Tablets
  • Relumina Relugolix 40mg Tablets
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BrandRelumina
Packaging TypeBox
Dose40 mg
Packaging Size10 x 10 Tablets
Product TypeAllopathic
Manufactured ByTakade Pharmaceutical company
Country of OriginMade in India
TreatmentProstate Cancer
Shelf Life2 Years
Storage30 Degree C (86 Degree F)

RELUMINA (Relugolix 40 Mg) is a prescription medicine used for the treatment of advanced prostate cancer. It is the only androgen deprivation therapy (ADT) medicine that is not an injection. IMPORTANT SAFETY INFORMATION What should I tell my healthcare provider before taking RELUMINA? Tell your healthcare provider about all of your medical conditions, including if you: Have any heart problems, including a condition called long QT syndrome. Are pregnant or plan to become pregnant. RELUMINA can harm your unborn baby and cause loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with RELUMINA and for 2 weeks after the last dose of RELUMINA. Are breastfeeding or plan to breastfeed. It is not known if RELUMINA passes into your breast milk. Tell your healthcare provider about all the medicines or treatments you receive, including: prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking RELUMINA with certain other medicines can affect how RELUMINA works or may cause side effects. You should not start or stop any medicine before you talk with your healthcare provider who prescribed RELUMINA. What are the possible side effects of RELUMINA? Serious side effects of RELUMINA include: Changes in the electrical activity of your heart (QT prolongation). Your healthcare provider may check your body salts (electrolytes) and the electrical activity of your heart during treatment with RELUMINA. Tell your healthcare provider right away if you get any signs or symptoms of QT prolongation, including: dizziness fainting feeling that your heart is pounding or racing (palpitations) chest pain Most common side effects of RELUMINA include: hot flushes increased blood sugar levels increased blood fat (triglyceride) levels muscle and joint pain decreased blood hemoglobin levels increased liver enzymes tiredness constipation diarrhea RELUMINA may cause other side effects including weight gain, decreased sex drive, and erectile function problems. RELUMINA may cause fertility problems in males, which may affect your ability to father children. Talk to your healthcare provider if this is a concern for you. These are not all the possible side effects of RELUMINA. Call your doctor for medical advice about side effects or if you have a side effect that bothers you or does not go away.  RELUMINA is a prescription medicine used in adults for the treatment of advanced prostate cancer. It is not known if RELUMINA is safe or effective in females or children.
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Diazoxide BP Eudemine Tablets 50 mg

Diazoxide BP Eudemine Tablets 50 mg
  • Diazoxide BP Eudemine Tablets 50 mg
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Packaging Size100 Tablets
BrandEudemine
ManufacturerFocus Pharma
CompositionDiazoxide BP
TreatmentIntractable Hypoglycaemia
FormTablet
Shelf life2 Years

Eudemine (Diazoxide 50 Mg) Tablets are used orally in the treatment of intractable hypoglycaemia.

Diazoxide also causes salt and water retention.

Hypoglycaemia: Eudemine administered orally is indicated for the treatment of intractable hypoglycaemia with severe symptoms from a variety of causes including: idiopathic hypoglycaemia in infancy, leucine-sensitive or unclassified; functional islet cell tumours both malignant and benign if inoperable, extra-pancreatic neoplasms producing hypoglycaemia; glycogen storage disease; hypoglycaemia of unknown origin.

Posology and method of administration
Hypoglycaemia: In hypoglycaemia, the dosage schedule of Eudemine tablets is determined according to the clinical needs and the response of the individual patient. For both adults and children a starting oral dose of 5mg/kg body weight divided into 2 or 3 equal doses per 24 hours will establish the patient's response and thereafter the dose can be increased until the symptoms and blood glucose level respond satisfactorily. Regular determinations of the blood glucose in the initial days of treatment are essential. The usual maintenance dose is 3 - 8mg/kg/day given in two or three divided doses.

Reduced doses may be required in patients with impaired renal function.

In children with leucine-sensitive hypoglycaemia, a dosage range of 15- 20mg/kg/day is suggested.

In adults with benign or malignant islet-cell tumours producing large quantities of insulin, high dosages of up to 1,000mg per day have been used.

Contraindications
In the treatment of hypoglycaemia, Eudemine is contraindicated in all cases which are amenable to surgery or other specific therapy.

Hypersensitivity to any component of the preparation or other thiazides.

Special warnings and precautions for use
In the treatment of hypoglycaemia it is necessary that the blood pressure be monitored regularly.

Retention of sodium and water is likely to necessitate therapy with an oral diuretic such as frusemide or ethacrynic acid. The dosage of either of the diuretics mentioned may be up to 1g daily. It must be appreciated that if diuretics are employed then both the hypotensive and hyperglycaemic activities of diazoxide will be potentiated and it is likely that the dosage of diazoxide will require adjustment downwards. In patients with severe renal failure it is desirable to maintain, with diuretic therapy, urinary volumes in excess of 1 litre daily. Hypokalaemia should be avoided by adequate potassium replacement.

Diazoxide should be used with caution in patients with cardiac failure or impaired cardiac reserve in whom sodium and water retention may worsen or precipitate congestive heart failure. A direct effect on myocardium and cardiac function cannot be excluded.

Diazoxide should be used with care in patients with impaired cardiac or cerebral circulation and in patients with aortic coarctation, aortic stenosis, arteriovenous shunt, heart failure or other cardiovascular disorders in which an increase in cardiac output could be detrimental.

Diazoxide should be administered with caution to patients with hyperuricaemia or a history of gout, and it is advisable to monitor serum uric acid concentration.

Whenever Eudemine is given over a prolonged period regular haematological examinations are indicated to exclude changes in white blood cell and platelet counts.

Also in children there should be regular assessment of growth, bone and psychological maturation.

The very rapid, almost complete protein binding of diazoxide requires cautious dosage to be used in patients whose plasma proteins may be lower than normal.
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Reviewed by 366 Users

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Very prompt in responding to my questions, answered all my questions. Took about 3 weeks to receive from India to the USA; which they sent me the tracking and overall it was a great experience.
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Product Name : Ledifos
Response time was very fast and the customer service excellent.The goods arrived on time and were reasonably priced.I can highly recommend Bull Pharmachem
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