Anti Cancer Medicines

Product Details:

Nintedanib, sold under the brand names BDR and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

Product Details:

Azacitidine (trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer.

Product Details:

Soranib (Sorafenib 200mg)  Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Soranib Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses Of Soranib Tablet:

• Liver cancer
• Kidney cancer
• Thyroid cancer

Benefits Of Soranib Tablet:
In Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Soranib Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

Side Effects Of Soranib Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Soranib:

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

How To Use Soranib Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soranib Tablet is to be taken empty stomach.HOW SORANIB TABLET WORKSSoranib Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Soranib Tablet. Please consult your doctor.
• Soranib Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks.
• Soranib Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Product Details:

Sorafenat (Sorafenib 200mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Sorafenat 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses Of Sorafenat Tablet:

• Liver cancer
• Kidney cancer
• Thyroid cancer

Benefits Of Sorafenat Tablet:
In Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Sorafenat 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

Side Effects Of Sorafenat Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Sorafenat:

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

How To Use Sorafenat Tablet::
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.

How Sorafenat Tablet Works:
Sorafenat 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Sorafenat 200mg Tablet.
• Sorafenat 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product Details:

Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.  Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.  Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.  Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment. 

Uses Of Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet: 
Blood cancer (Chronic myeloid leukaemia) 

Benefits OF Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet:
In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dasatinib (20 Mg, 50 Mg, 70 Mg) Abdominal pain Anemia (low number of red blood cells) Breathing problems Fatigue Fever Headache Infection Low blood platelets Musculoskeletal (bone, muscle or joint) pain Nausea Rash Vomiting.

How to use Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet: 
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time. 

How Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet Works: 
Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
 
Safety Advice:
It is not known whether it is safe to consume alcohol with Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet. 

Product Details:

Varenicline (trade name Chantix and Champix) is a medication used for smoking cessation. Varenicline is also used for the treatment of dry eye disease.

The most common side-effects include nausea (feeling sick), insomnia (difficulty sleeping), abnormal dreams, headache and nasopharyngitis (inflammation of the nose and throat).

It is a high-affinity partial agonist for nAChRα4β2, a subtype of nicotinic acetylcholine receptor (nAChR) that leads to the release of the neurotransmitter dopamine in the nucleus accumbens (reward center of the brain) when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation. In this respect it is similar to cytisine and different from the nicotinic antagonist bupropion and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. It is estimated that varenicline successfully helps one of every eleven people who smoke remain abstinent from tobacco at six months.

It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 275th most commonly prescribed medication in the United States, with more than 1 million prescriptions

Product Details:

XTANDI (Enzalutamide 40mg) is a prescription medicine used to treat men with prostate cancer that: 
No longer responds to a hormone therapy or surgical treatment to lower testosterone or has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone. It is not known if XTANDI is safe and effective in females or children. XTANDI is an androgen receptor inhibitor. Androgens are a group of hormones that includes testosterone. Androgen receptor inhibitors interfere with the connection between androgens and androgen receptors. This can help slow cancer cell growth

Important Safety Information
What should I tell my doctor before taking XTANDI?
Tell your doctor about all your medical conditions, including if you:Have a history of seizures, brain injury, stroke, or brain tumors.Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant.Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breast feeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor.

How should I take XTANDI?
Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI.

Product Details:

Glenza Capsule (Enzalutamide 40 mg) is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Glenza Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.Enzalutamide Glenza 40mg Capsules Uses : 

Enzalutamide 40mg is utilized for the treatment of metastatic maiming safe prostate growth (prostate cancer that is impervious to therapeutic or surgical medications that lower testosterone). This medication likewise keeps the androgens from working inside the prostate disease cells. 

 

Indian Enzalutamide Capsules Side Effects: 
All meds may cause symptoms, however many individuals have no, or minor, reactions. Check with your specialist if any of these most COMMON reactions hold on or wind up noticeably annoying: 

• Icy like manifestations (eg, hack, runny or stuffy nose, wheezing, sore throat); the runs; tipsiness; cerebral pain; hot flashes; mellow back, bone, joint, or, then again muscle torment; tiredness; inconvenience resting; shortcoming. 
• Look for medicinal consideration immediately if any of these SEVERE reactions happen: Serious unfavorably susceptible responses (rash; hives; tingling; trouble breathing; snugness in the chest; swelling of the mouth, face, lips, or tongue); nervousness; back torment with leg deadness or shortcoming; changes in the measure of pee delivered; perplexity or issues thinking obviously; the diminished feeling of touch; sentiment shivering, consuming, pricking, or deadness of the skin; fever, chills, or determined sore throat; visualizations; memory issues; muscle throbs or shortcoming; pink or red pee; seizures; 
• An extreme or diligent migraine; shortness of breath; swelling of the hands, arms, legs, or feet. 

Product Details:

Bdenza  (Enzalutamide40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Bdenza 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Bdenza 40 mg Capsule is used to treat castrate-resistant prostate cancer (CRPC), a stage where prostate cancer keeps growing even when there are very low levels of testosterone in the body. It is mainly used in patients whose disease has progressed on or after Docetaxel therapy. This medicine is not recommended for use in females, children, and adolescents.

Benefits Of Bdenza Capsule:
In Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side Effects  Of Bdenza Capsule:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Bdenza

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

Product Details:

Azel (Enzalutamide 40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Azel 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Benefits Of Azel Capsule:
In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Azel 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side Effects Of Azel Capsule:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

How To Use Azel Capsule:
Take this medicine in the dose and duration as advised by your doctor. Azel 40mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Azel Capsule Works:
Azel 40mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Product Details:

Obnyx (Enzalutamide 40mg) is FDA approved generic oncology drug that is used to treat advanced forms of Prostate cancer, non-metastatic castration-resistant prostate cancer (nmCRPC).

A company statement declared that this is a drop of 70%, in comparison to the existing cost of therapy in India.

As per statement, the current MRP of Enzalutamide drug in India ranges from Rs. 70000 to Rs 80000 for a monthly therapy and can be a huge financial burden for the elderly patients as they need to continue the therapy for a long period of time. This price reduction will benefit many prostate cancer patients to adhere to the treatment.
The drug, named Enzalutamide, launched under the brand name Obnyx 40mg, will be available in soft gelatin capsules at a monthly treatment cost aprox of 357 US$.
In the U.S, Enzalutamide is sold under the Xtandi brand name.

Obnyx 40 mg capsule is usually taken as 4 capsules (4 * 40 mg = 160 mg), once a day at the same time.

According to the company statement, 1/9 Indian males have the threat of suffering from prostate cancer, which is almost 60% of males above the age of sixty-five.

Prostate cancer remains one of the major cancers in India. The drug assists the patients by decreasing the androgen hormones in their prostate glan. Enzalutamide is used to treat prostate cancer that has spread to other parts of the body in men and who have been helped by certain medical and surgical treatments that decrease testosterone levels.

Enzalutamide is a type of hormone therapy. It is a treatment for prostate cancer that has spread to other parts of the body (advanced prostate cancer)

Product Details:

Indenza 40 mg (Enzalutamide) is an androgen receptor (AR) inhibitor indicated for patients suffering from prostate cancer types such as,

• Metastatic castration-resistant prostate cancer where other chemotherapy options (docetaxel) did not work. (cancer that lowers the growth of testosterone, a male hormone)
• Metastatic castration-sensitive prostate cancer where other hormonal therapy did not work (cancer that spreads to other parts of the body)

Peculiar properties of Indenza 40 mg (Enzalutamide) that helps in slowing down the growth of prostate cancer,

• Obstructs the communication tool of cancer cells (AR signaling i.e. binding with androgen receptor and interaction with DNA)
• Hinders the unwanted growth (Cell proliferation) of androgen (testosterone)
• Induces the act of self-destruction of cells (Apoptosis)
• Reduces the risk of progression and death
• Postpones the requirement of chemotherapy

Administration of Indenza 40 mg (Enzalutamide):

Indenza 40 mg (Enzalutamide) is given orally in a 160 mg dosage (4×40 mg) once in 24 hours with or without food. If patients experience any sort of side-effects, the dosage can be modified and reduced to 120 mg (3×40 mg) or 80 mg (2×40 mg).

Once swallowed, enzalutamide is readily soluble (bio-available) in the body within 3 hours. It is metabolized in the liver and then distributed throughout the region of cancer with a high binding affinity (97%) to cancer cells. Once enzalutamide completes its activities, more than 50% of the dose is expelled from the body in between 3 to 11 days.

When should Indenza 40 mg (Enzalutamide) be avoided or used cautiously?

• If patients have a history of or experience sudden unwarranted changes in behaviour caused due to disturbances in the brain (Seizures)
• If patients are confirmed with symptoms like headache, impaired vision and low blood pressure (Posterior reversible encephalopathy syndrome)
• If patients are seen with kidney diseases (severe renal impairment and end-stage renal disease)
• If patients show signs of severe disease of the liver
• If patients are seen with a relative risk of heart diseases
• If patients are allergic to dosage and show symptoms like tongue, lip, or pharyngeal swelling (edema)
• If patients are intolerant to lactose

Side-effects of Indenza 40 mg (Enzalutamide):
Most common side-effects:

• Tiredness (Fatigue)
• Pain in the back, muscles, bones and joints
• Diarrhea
• Weakness in the muscles
• Dizziness
• Swelling (edema) in the hands and legs
• Severe headache
• Cold-like symptoms
• Anxiety or stress

Other side-effects:

• Discoloured urine in pink or red colour (Hematuria)
• Rashes on skin
• Trouble in falling asleep (insomnia)
• Trouble in breathing (pneumonia)
• Weakness in the legs
• Pain in the lower back
• High blood pressure (Hypertension)
• Burning or numbness of skin (paresthesia)
• Excitement or confusion
• Loss of memory
• Nightmares

Product Details:

Lenalidomide  (5mg, 10mg , 25mg) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lenalidomide  should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lenalidomide  is safe and effective in children.What is the most important information I should know about Lenalidomide  ?Before you begin taking Lenalidomide  , you must read and agree to all of the instructions in the Lenalidomide  REMS program. Before prescribingLenalidomide  , your healthcare provider will explain the Lenalidomide  REMS program to you and have you sign the Patient-Physician Agreement Form.
Lenalidomide  may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not takeLenalidomide  .
Lenalidomide  is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lenalidomide  has not been tested in pregnant females. Lenalidomide  has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before startingLenalidomide  While taking Lenalidomide  During any breaks (interruptions) in your treatment with Lenalidomide  For at least 4 weeks after stopping Lenalidomide  Females who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stoppingLenalidomide  .Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment withLenalidomide  .If you had unprotected sex or if you think your birth control has failed, stop taking Lenalidomide  immediately and call your healthcare provider right away.If you become pregnant while takingLenalidomide  , stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lenalidomide  during pregnancy, or if their male partner takes Lenalidomide  and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lenalidomide  can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while takingLenalidomide  , during any breaks (interruptions) in your treatment withLenalidomide  , and for up to 4 weeks after stoppingLenalidomide  .Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.

Additional Information:

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Product Details:

Cyendiv (Nintedanib  100mg , 150mg ) is a prescription medicine used:

• To treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).
• To treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).
• To slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).
• It is not known if Cyendiv is safe and effective in children.

Product Details:

Invista (Dasatinib 70mg)Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Invista 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Invista Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of Invista Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Invista 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Invista Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. 

Safety Advice:

• It is not known whether it is safe to consume alcohol with Invista 70mg Tablet. 
• Invista 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• Invista 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• Invista 70mg Tablet may cause side effects which could affect your ability to drive.
• Take special care when driving in case you experience side effects such as dizziness and blurred vision with Invista 70mg Tablet.
• Invista 70mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Invista 70mg Tablet may not be needed in these patients. 

Product Details:

Sorafekast (Sorafenib 200mg)GENERIC NAME:Sorafenib Tablets LP. 200 mg
QUALITATIVE AND QUANTITATIVE COMPOSITION:Each film-coated tablet contains: Sorafenlb tosylate IP Equivalent to Sorafeni x me Exclplents …
Colours: Feric oxide Red usr. NF. Titanium Dioxide IP.
The used are rystal Ge G Sodium, Sodium Lauryi Sulphate, Magnesium stearate, Titanium Dioxide, Macrogol/PEG and Ferric Oxide Red’.
DOSAGE FORM AND STRENGTH:-Oral (Fllm-coated tablets) and 200 mg
4. CLINICAL PARTICULARS:
4.1 Therapeutic Indication
For the treatment of patients with advanced renal cell carcinoma (RCC).
For hepatocellular Carcinoma (HCC).
For the treatment of patients with locally advanced or metastatic differentiated thyroid carcinoma
(DTC) refractory to radioactive iodine.
4.2 Posology and mathod of administration
Sorafenib treatment should be supervised by a physician experienced in the use of anticancer therapies.
The recommended dose of sorafenib in adults is 400 mg (two tablets of 200 mg) twice daily (equivalent to a total dally dose of 800 mg).
Treatment should continue as long as clinical benefit is observed or until unacceptable toxicity occurs.
When dose Is ry during the (HCC) and advanced renal cell carcinoma (RCC), the sorafenib dose snow be reduced to two tablets of 200 mg sorafenib once dally.
When dose ion is Y¥ during the of diffe i thyroid (DTC), the sorafenib dose should be reduced to 600 mg sorafenib daily in divided doses (two tablets of 200 mg and one tablet of 200 mg twelve hours apart). If additional dose reduction is necessary, sorafenib may be reduced to 400 mg sorafenib daily in divided doses (two tablets of 200 mg twelve hours apart), and If necessary further reduced to one tablet of 200mg once daily.
Paediatric population
The safety and efficacy of sorafenib in children and adolescents aged < 18 years have not yet been established. No data are available.
Elderly population
No dose adjustment Is required In the elderly (patients above 65 years of age).
Renal impairment
No dese adjustment Is required In patients with mild, moderate or severe renal Impairment. No data Is available in patients requiring dialysis. Monitoring of fluid balance and electrolytes in patients at risk of renal dysfunction is advised.
Hepatic impairment
No dose adjustment is required in patients with Child Pugh A or B (mild to moderate) hepatic impairment.
No data Is avallable on patients with Child Pugh C (severe) hepatic Impairment. may require temporary interruption or dose reduction
For oral use.
It is recommended that sorafenib should be administered without food or with a low or moderate fat meal. If the patient Intends to have a high-fat meal, sorafenib tablets should be taken at least 1 hour before or 2 hours after the meal. The tablets should be swallowed with a glass of water.

Product Details:

Pivikto (Alpelisib 150mg) tablets is contraindicated in patients with severe hypersensitivity to it or any of its componentsIndicationPivikto (Alpelisib 150mg) tablets is indicated in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or after an endocrine-based regimen.Important Safety InformationAlpelisib is contraindicated in patients with severe hypersensitivity to it or any of its components.Severe Hypersensitivity: Severe hypersensitivity reactions, including anaphylaxis and anaphylactic shock, can occur in patients treated with Pivikto . Severe hypersensitivity reactions were manifested by symptoms including, but not limited to, dyspnea, flushing, rash, fever, or tachycardia. The incidence of grade 3 and 4 hypersensitivity reactions was 0.7%. Advise patients of the signs and symptoms of severe hypersensitivity reactions. Permanently discontinue Alpelisib in the event of severe hypersensitivity.Severe Cutaneous Adverse Reactions (SCARs): SCARs including Stevens-Johnson syndrome (SJS), erythema multiforme (EM), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) can occur in patients treated with Pivikto . In the SOLAR-1 study, SJS and EM were reported in 0.4% and 1.1% of patients, respectively. DRESS was reported in patients in the postmarketing setting. If signs or symptoms of SCARs occur, interrupt Alpelisib until the etiology of the reaction has been determined. Consultation with a dermatologist is recommended.If a SCAR is confirmed, permanently discontinue Pivikto . Do not reintroduce Alpelisib in patients who have experienced previous SCARs during Alpelisib treatment. If it is not confirmed, Alpelisib may require dose modifications, topical corticosteroids, or oral antihistamine treatment.Advise patients of the signs and symptoms of SCARs (eg, a prodrome of fever, flu-like symptoms, mucosal lesions, progressive skin rash, or lymphadenopathy).Hyperglycemia: Severe hyperglycemia, including ketoacidosis, can occur in patients treated with Pivikto . Hyperglycemia was reported in 65% of patients treated with Pivikto . Grade 3 (FPG >250-500 mg/dL) and grade 4 (FPG >500 mg/dL) hyperglycemia were reported in 33% and 3.9% of patients, respectively. Ketoacidosis was reported in 0.7% of patients (n=2) treated with Pivikto .Before initiating treatment with Pivikto , test fasting plasma glucose (FPG), HbA1c, and optimize blood glucose. After initiating treatment with Pivikto , monitor fasting glucose (FPG or fasting blood glucose) at least once every week for the first 2 weeks, then at least once every 4 weeks, and as clinically indicated. Monitor HbA1c every 3 months and as clinically indicated. If a patient experiences hyperglycemia after initiating treatment with Pivikto , monitor fasting glucose as clinically indicated, and at least twice weekly until fasting glucose decreases to normal levels. During treatment with antidiabetic medication, continue monitoring fasting glucose at least once a week for 8 weeks, followed by once every 2 weeks and as clinically indicated. Consider consultation with a health care practitioner with expertise in the treatment of hyperglycemia and counsel patients on lifestyle changes.The safety of Alpelisib in patients with type 1 and uncontrolled type 2 diabetes has not been established as these patients were excluded from the SOLAR-1 trial. Patients with a medical history of type 2 diabetes were included. Patients with a history of diabetes mellitus may require intensified diabetic treatment. Closely monitor patients with diabetes.

Product Details:

Dasanat (Dasatinib 50mg) Tablet is used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a type of blood cancer that occurs due to a chromosome abnormality. It is also used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous and immature lymphoblasts in large quantities. This medicine is not recommended for patients below 1 year of age.Side effectsMajor & minor side effects for Dasanat 50 TabletBody aches or PainBurning, numbness, tingling in the arms and feetChest painChillsCoughDizzinessHeadacheWeight gainFeverIrritation of throatUlcers or white spots in the mouthNauseaIrregular breathingIncreased sweatingUses of Dasanat 50 TabletWhat is it prescribed for?Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML)This medicine is used for the treatment of advanced and newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase in patients who have acquired resistance or intolerance to prior therapy.Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)This medicine is used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous lymphocytes. It is used in patients who have acquired resistance or intolerance to prior therapy. WarningsWarnings for special populationPregnancyThis medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Breast-feedingThis medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.General warningsGastrointestinal disordersThis medicine should be used with caution in patients having a pre-existing disorder of the stomach or the intestine due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.Driving or Operating machineryUse of this medicine may cause dizziness and blurring of vision. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.Bonemarrow suppressionThis medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Internal bleeding or hemorrhageThis medicine should be used with caution due to the increased risk of internal bleeding or hemorrhages. Any symptoms such as unusual bleeding or bruising, black or tarry stools, vomiting up blood, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Risk of infectionsUse of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while taking this medicine.

Product Details:

Nexavar (Sorafenib 200mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer. Nexavar 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF NEXAVAR TABLET Liver cancer Kidney cancer Thyroid cancer BENEFITS OF NEXAVAR TABLET In Liver cancer Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Nexavar 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery. In Kidney cancer Nexavar 200mg Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. In Thyroid cancer Thyroid is a butterfly-shaped gland located at the base of your neck. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight. Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first. Nexavar 200mg Tablet restricts the oxygen supply of the cancer cells and stops its growth as well as further spread. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. Show Less SIDE EFFECTS OF NEXAVAR TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

Product Details:

REVLIMID (lenalidomide 5mg 10mg 25mg) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). REVLIMID should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if REVLIMID is safe and effective in children.What is the most important information I should know about REVLIMID?Before you begin taking REVLIMID, you must read and agree to all of the instructions in the REVLIMID REMS® program. Before prescribing REVLIMID, your healthcare provider will explain the REVLIMID REMS program to you and have you sign the Patient-Physician Agreement Form.
REVLIMID may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take REVLIMID.
REVLIMID is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. REVLIMID has not been tested in pregnant females. REVLIMID has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting REVLIMIDWhile taking REVLIMIDDuring any breaks (interruptions) in your treatment with REVLIMIDFor at least 4 weeks after stopping REVLIMIDFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping REVLIMID.Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with REVLIMID.If you had unprotected sex or if you think your birth control has failed, stop taking REVLIMID immediately and call your healthcare provider right away.If you become pregnant while taking REVLIMID, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take REVLIMID during pregnancy, or if their male partner takes REVLIMID and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
REVLIMID can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking REVLIMID, during any breaks (interruptions) in your treatment with REVLIMID, and for up to 4 weeks after stopping REVLIMID.Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.Do not donate sperm while taking REVLIMID, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping REVLIMID. If a female becomes pregnant with your sperm, the baby may be exposed to REVLIMID and may be born with birth defects.

Product Details:

Retevmo (Selpercatinib 80mg) is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in adults with non-small cell lung cancer (NSCLC) that has spread, adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy), and adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working. Your healthcare provider will perform a test to make sure that Retevmo is right for you. It is not known if Retevmo is safe and effective in children younger than 12 years of age. Retevmo was approved based on the percentage of patients whose tumor size shrank or disappeared after treatment and how long the response lasted. Studies are ongoing to confirm the benefit of Retevmo for this use. Retevmo may affect both healthy cells and tumor cells, which can result in side effects, some of which can be serious. Important Facts About RETEVMO® (reh-TEHV-moh). It is also known as selpercatinib. RETEVMO is a prescription medicine that is used to treat certain cancers caused by an abnormal gene, called RET, in: adults with non-small cell lung cancer (NSCLC) that has spread. adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread, who need a medicine that can be taken by mouth or injection. adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread, who need a medicine that can be taken by mouth or injection, and who have received radioactive iodine and it did not work or is no longer working. Your doctor will perform a test to make sure that RETEVMO is right for you. It is not known if RETEVMO is safe and effective in children younger than 12 years of age. Warnings RETEVMO may cause serious side effects, including: Liver problems: Liver problems (higher levels of liver enzymes) are common with RETEVMO and may sometimes be serious. Your doctor will do blood tests before and during treatment with RETEVMO to check for liver problems. Tell your doctor right away if you get any of the following symptoms of liver problems during treatment: yellowing of your skin or the white part of your eyes (jaundice) dark, “tea-colored” urine sleepiness bleeding or bruising loss of appetite nausea or vomiting pain on the upper right side of your stomach area If you develop liver problems while taking RETEVMO, your doctor may lower your dose, stop treatment for a while, or stop treatment permanently. High blood pressure (hypertension): High blood pressure is common with RETEVMO. It may sometimes be serious. You should check your blood pressure regularly during treatment with RETEVMO. Tell your doctor if you get any of the following symptoms during treatment: confusion headaches shortness of breath dizziness chest pain Heart rhythm changes (QT prolongation) can happen. These may be serious. RETEVMO may cause very slow, very fast, or irregular heartbeats. Tell your doctor right away if you get any of the following symptoms during treatment: loss of consciousness fainting dizziness a change in the way your heart beats (heart palpitations) Bleeding problems: RETEVMO can cause bleeding, which can be serious and may lead to death. Tell your doctor if you have any signs of bleeding during treatment, including:

Product Details:

Lynide ( Lynideomide 5mg ,10mg ,25mg)is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lynide should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lynide is safe and effective in children.What is the most important information I should know about Lynide?Before you begin taking Lynide, you must read and agree to all of the instructions in the Lynide REMS program. Before prescribing Lynide, your healthcare provider will explain the Lynide REMS program to you and have you sign the Patient-Physician Agreement Form.
Lynide may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take Lynide.
Lynide is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lynide has not been tested in pregnant females. Lynide has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting LynideWhile taking LynideDuring any breaks (interruptions) in your treatment with LynideFor at least 4 weeks after stopping LynideFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping Lynide.Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with Lynide.If you had unprotected sex or if you think your birth control has failed, stop taking Lynide immediately and call your healthcare provider right away.If you become pregnant while taking Lynide, stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lynide during pregnancy, or if their male partner takes Lynide and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lynide can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while taking Lynide, during any breaks (interruptions) in your treatment with Lynide, and for up to 4 weeks after stopping Lynide.Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.Do not donate sperm while taking Lynide, during any breaks (interruptions) in your treatment, and for 4 weeks after stopping Lynide. If a female becomes pregnant with your sperm, the baby may be exposed to Lynide and may be born with birth defects.Men: If a female becomes pregnant with your sperm, you should call your HCP right away.

Additional Information:

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Product Details:

• Azacitidine For Injection is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS usually have problems such as infections, anemia, and easy bleeding/bruising. Azacitidine is a chemotherapy drug.
• It works by helping your bone marrow grow normal blood cells so you will need fewer blood transfusions. Azacitidine also kills abnormal blood cells that have grown too fast and do not work properly.

Product Details:

DYRONIB (Dasatinib 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
DYRONIB 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. 

Uses Of Sprycel Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Sprycel Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DYRONIB 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Sprycel Tablet:
TMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Sprycel Abdominal pain Anemia (low number of red blood cells)Breathing problems, Fatigue, Fever,Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain Nausea Rash Vomiting.

How To Use Sprycel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DYRONIB 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sprycel Tablet Works:
DYRONIB 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with DYRONIB 70mg Tablet.
• DYRONIB 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• DYRONIB 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• DYRONIB 70mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with DYRONIB 70mg Tablet.

Product Details:

DASATRUE(Dasatinib 70 mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
DASATRUE 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of DASATRUE Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of DASATRUE Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASATRUE 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of DASATRUE Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dasature Abdominal pain Anemia (low number of red blood cells)Breathing problemsFatigue, Fever, Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain Nausea, Rash, Vomiting.

How To Use DASATRUE Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASATRUE 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How DASATRUE Tablet Works:
DASATRUE 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with DASATRUE 70 mg Tablet. 
• DASATRUE 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• DASATRUE 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• DASATRUE 70 mg Tablet may cause side effects which could affect your ability to drive.

Product Details:

PEG L- ASPATERO (Peg L-Asparaginase 3750 IU) is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. Peg L-Asparaginase Injection 3750 IU is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effect of this medicine Peg L-Asparaginase Injection 3750 IU includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar level, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well. This medicine may lower your body’s resistance and increasing the susceptibility to infections. Infections can sometimes be life threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Nintib (Nintedanib  100mg , 150mg) is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Nintib is safe and effective in children.What are the possible side effects of Nintib?Nintib may cause serious side effects, including:See “What is the most important information I should know about Nintib?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Nintib.diarrhea, nausea, and vomiting. While you are taking Nintib, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Nintib may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Nintib may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Nintib are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

Indications:
Idiopathic Pulmonary FibrosisNintib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeNintib is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].Systemic Sclerosis-Associated Interstitial Lung DiseaseNintib is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

SPNIB (Dasatinib 70mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
SPNIB 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. 

Uses Of Spinab Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Spinab Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. SPNIB 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Spinab Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of SPNIBAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomiting

How To Use Spinab Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SPNIB 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Spinab Tablet Works:
SPNIB 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with SPNIB 70 mg Tablet. 
• SPNIB 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• SPNIB 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• SPNIB 70 mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with SPNIB 70 mg Tablet.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Sprycel(Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.Sprycel 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Sprycel Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Sprycel Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Sprycel 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Sprycel Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Sprycel Abdominal pain, Anemia (low number of red blood cells)Breathing problems, Fatigue, Fever, Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain, Nausea, Rash, Vomiting.

How To Use Sprycel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sprycel 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sprycel Tablet Works:
Sprycel 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Sprycel 20mg 50mg 70mg Tablet. 
• Sprycel 20mg 50mg 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• Sprycel 20mg 50mg 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

ZEJULA (Niraparib 100mg) is a prescription medicine used for the:maintenance treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.maintenance treatment of adults with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that comes back. ZEJULA is used after the cancer has responded (complete or partial response) to treatment with platinum-based chemotherapy.treatment of adults with advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who have been treated with 3 or more prior types of chemotherapy and who have tumors with:  a certain BRCA gene mutation, orgene mutation problems and who have progressed more than 6 months after their last treatment with platinum-based chemotherapy.Your healthcare provider will perform a test to make sure that ZEJULA is right for you.It is not known if ZEJULA is safe and effective in children.
Important Safety InformationZEJULA may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during treatment with ZEJULA. MDS or AML may lead to death.
Symptoms of low blood cell counts (low red blood cells, low white blood cells, and low platelets) are common during treatment with ZEJULA. They can be a sign of serious bone marrow problems, including MDS or AML. These symptoms may include the following:
Weakness
Feeling tired
Weight loss
Frequent infections
Fever
Shortness of breath
Blood in urine or stool
Bruising or bleeding more easily
Your doctor will do blood tests to check your blood cell counts before treatment with ZEJULA. You will be tested weekly for the first month of treatment with ZEJULA, monthly for the next 11 months of treatment, and from time to time afterward.
High blood pressure is common during treatment with ZEJULA, and it can become serious. Your doctor will check your blood pressure and heart rate at least weekly for the first two months, then monthly for the first year, and as needed thereafter during your treatment with ZEJULA.
Posterior reversible encephalopathy syndrome (PRES) is a condition that affects the brain and may happen during treatment with ZEJULA. If you have headache, vision changes, confusion, or seizure, with or without high blood pressure, please contact your doctor.
Before starting to take ZEJULA, tell your doctor about all of your medical conditions, including if you:
Have heart problemsHave liver problemsHave high blood pressureAre allergic to FD&C Yellow No. 5 (tartrazine) or aspirin. ZEJULA capsules contain tartrazine, which may cause allergic-type reactions (including bronchial asthma) in certain people, especially people who also have an allergy to aspirin
Are pregnant or plan to become pregnant. ZEJULA may harm an unborn baby and may cause loss of pregnancy (miscarriage)If you are able to become pregnant, you should use effective birth control (contraception) during treatment with ZEJULA and for 6 months after taking the last dose of ZEJULAIf you are able to become pregnant, your doctor may perform a pregnancy test before you start treatment with ZEJULAYou should tell your doctor right away if you become pregnantAre breastfeeding or plan to breastfeedZEJULA may harm your baby. You should not breastfeed your baby during treatment with ZEJULA and for 1 month after taking the last dose of ZEJULATell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Product Details:

Mitomycin 40 (Mitomycin 40mg) Injection is used in the treatment of certain kinds of cancer of pancreas, breast, lung, and stomach. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed.

Mitomycin 40mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, loss of appetite, nausea, and vomiting.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder.  This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses Of Mitomycin Injection:

• Pancreatic cancer
• Breast cancer
• Non-small cell lung cancer
• Stomach cancer

Benefits Of Mitomycin Injection:

In Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Mitomycin 40mg Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

Product Details:

Ibrunat (Ibrutinib 140mg)contains the Drug/Molecule called “Ibrutinib”. Ibrunat is a small molecule drug that is used to bind permanently to a protein called “Bruton’s tyrosine kinase (BTK)” which is important in B cells.

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

How Ibrunat Ibrutinib 140 mg Capsule Works

Ibrutinib which is the active ingredient in Ibrunat 140 mg capsules, works in a manner that it blocks the activity of a specific protein called “Bruton’s tyrosine kinase”, or BTK.

Bruton’s tyrosine kinase is a protein that is found in your B cells and it sends “signals” to the other parts of the body that help B cells to survive and multiply.

But these generic ibrunat capsules block BTK & help in killing and reducing the number of cancerous B-cells. Therefore, this stops or slows the progression of cancer.

How to Take Ibrunat Capsule
It is prescribed to take Ibrunat 140 mg once in a day at about the same time every day. The dosage and duration of treatment depends on the type of blood cancer, the age of the patient, and on how severe the condition of the patient.

Moreover, it also depends on “how the patient’s body reacts to the first dose.” The Natco Ibrunat Capsules should be taken orally with a glass of water. Please remember to not to open, crush, or chew the capsules.

Side Effects of Ibrunat Capsules
Ibrunat can cause side effects like:

• Bleeding
• Leukostasis
• Infections
• Decrease the blood cell counts
• Heart problems or Liver problems.

There are chances of occurring the new cancers in people taking Ibrunat, including skin cancer & other cancers.

The most common side effects may include:

• Pneumonia
• Upper respiratory tract infection
• Diarrhea
• Feeling very tired
• nausea
• headache
• swollen hands
• ankles or feet
• being short of breath
• dizziness
• fainting
• constipation and infected nose.

Interactions with other drugs

• Some antiplatelet drugs like “Clopidogrel”, “NSAIDs like Ibuprofen / Naproxen”, “Blood thinners like Warfarin / Dabigatran” can cause bleeding / bruising with Ibrunat capsules.
• The drug called aspirin can increase the risk of bleeding if it is used with Ibrunat Ibrutinib.
• And lastly, the azole antifungals drugs such as “Itraconazole”, “Ketoconazole” can affect the removal of Ibrunat from body.

Overdose 

• You shouldn’t take more than prescribed dose.
• The patients who have received doses higher than the recommended quantity should be carefully monitored. And most importantly, don’t ever take extra dose for the missed dose.

Precaution 
The patients taking ibrunat shouldn’t take it with grapefruit or Seville oranges. Which includes eating these fruits, drinking the juice, or taking the supplements that mat contain these fruits. It is prescribed not to take these fruits because these can increase the amount of Ibrunat in blood.

Product Details:

OFEV (nintedanib 100mg 150mg) is a prescription medicine used:

• To treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).
• To treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).
• To slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD). It is not known if OFEV is safe and effective in children.

Indications:

• Idiopathic Pulmonary  is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
• Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeOFEV is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].
• Systemic Sclerosis-Associated Interstitial Lung DiseaseOFEV is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Dosage And Administration:
Testing Prior To OFEV Administration Conduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with OFEV 

Recommended Dosage

• The recommended dosage of OFEV is 150 mg twice daily administered approximately 12 hours apart.
• OFEV capsules should be taken with food 

Product Details:

Eligard (Leuprolide 22.5 Mg) Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Eligard Depot 22.5mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF ELIGARD INJECTION Treatment of Prostate cancer Treatment of Endometriosis Treatment of Uterine fibroids Treatment of Precocious puberty (premature puberty).

Benefits Of Eligard Injection:
In Treatment of Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Eligard Depot 22.5mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate. In Treatment of Endometriosis Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Eligard Depot 22.5mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis. In Treatment of Uterine fibroids Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Eligard Depot 22.5mg Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further. In Treatment of Precocious puberty (premature puberty) When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Eligard Depot 22.5mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. 

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

VIDAZA (Azacitidine 100 Mg) is indicated for treatment of patients with the following French-American-British (FAB) Myelodysplastic Syndrome Subtypes: refractory anemia (RA) or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL).

Dosage And Administration:
First Treatment Cycle The recommended starting dose for the first treatment cycle, for all patients regardless of baseline hematology laboratory values, is 75 mg/m2 subcutaneously or intravenously, daily for 7 days. Premedicate patients for nausea and vomiting. Obtain complete blood counts, liver chemistries and serum creatinine prior to the first dose. Dosage Adjustment Based On Serum Electrolytes And Renal Toxicity If unexplained reductions in serum bicarbonate levels to less than 20 mEq/L occur, reduce the dosage by 50% for the next course. Similarly, if unexplained elevations of BUN or serum creatinine occur, delay the next cycle until values return to normal or baseline and reduce the dose by 50% for the next course.

Warning And Precautions:
Use In Geriatric Patients Azacitidine and its metabolites are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, select the dose carefully and monitor renal function.  Use In Specific Populations]. Preparation Of VIDAZ VIDAZA is a cytotoxic drug. Follow applicable special handling and disposal procedures. 1 The VIDAZA vial is single-dose and does not contain any preservatives. Discard unused portions of each vial properly [see HOW SUPPLIED]. Do not save any unused portions for later administration. Instructions For Subcutaneous Administration Reconstitute VIDAZA aseptically with 4 mL sterile water for injection. Inject the diluent slowly into the vial. Vigorously shake or roll the vial until a uniform suspension is achieved. The suspension will be cloudy. The resulting suspension will contain azacitidine 25 mg/mL. Do not filter the suspension after reconstitution. Doing so could remove the active substance. Preparation For Immediate Subcutaneous Administration For doses requiring more than 1 vial, divide the dose equally between the syringes (e.g., dose 150 mg = 6 mL, 2 syringes with 3 mL in each syringe) and inject into two separate sites. Due to retention in the vial and needle, it may not be feasible to withdraw all of the suspension from the vial. The product may be held at room temperature for up to 1 hour, but must be administered within 1 hour after reconstitution. Preparation For Delayed Subcutaneous Administration The reconstituted product may be kept in the vial or drawn into a syringe. For doses requiring more than 1 vial, divide the dose equally between the syringes (e.g., dose 150 mg = 6 mL, 2 syringes with 3 mL in each syringe) and inject into two separate sites. Due to retention in the vial and needle, it may not be feasible to withdraw all of the suspension from the vial. The product must be refrigerated immediately. When VIDAZA is reconstituted using water for injection that has not been refrigerated, the reconstituted product may be held under refrigerated conditions (2°C -8°C, 36°F -46°F) for up to 8 hours. When VIDAZA is reconstituted using refrigerated (2°C -8°C, 36°F -46°F) water for injection, the reconstituted product may be stored under refrigerated conditions (2°C -8°C, 36°F -46°F) for up to 22 hours. After removal from refrigerated conditions, the suspension may be allowed to equilibrate to room temperature for up to 30 minutes prior to administration.

Product Details:

DASASHEEL (Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

DASASHEEL 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Dasasheel Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of Dasasheel Tablet:

• In Blood cancer (Chronic myeloid leukaemia)
• Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASASHEEL 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

How To Use Dasasheel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASASHEEL 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dasasheel Tablet Works:
DASASHEEL 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Product Details:

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

Product Details:

Lenalid (Lenalidomide 5mg ,10mg,  25mg)is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lenalid should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lenalid is safe and effective in children.

What is the most important information I should know about Lenalid?
Before you begin taking Lenalid, you must read and agree to all of the instructions in the Lenalid REMS program. Before prescribing Lenalid, your healthcare provider will explain the Lenalid REMS program to you and have you sign the Patient-Physician Agreement Form.

Lenalid may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not take Lenalid.

Lenalid is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lenalid has not been tested in pregnant females. Lenalid has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before starting LenalidWhile taking LenalidDuring any breaks (interruptions) in your treatment with LenalidFor at least 4 weeks after stopping LenalidFemales who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling. Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stopping Lenalid. Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment with Lenalid. If you had unprotected sex or if you think your birth control has failed, stop taking Lenalid immediately and call your healthcare provider right away. If you become pregnant while taking Lenalid, stop taking it right away and call your healthcare provider.

Product Details:

Dasakast (dasatinib 70mg) is an oral drug indicated for patients suffering from blood cancer in both adults and children. Specifically, dasakast 50 mg (dasatinib) is used in adults with Chronic myeloid leukemia (CML) in a long-lasting (chronic) phase of the disease. Dasatinib belongs to the class of medicine known as kinase inhibitors that works its action by:

• Firstly, blocking the activities of abnormal protein
• Secondly, hindering the multiplication of cancer cells (cell-proliferation)
• Lastly, reducing blood flow to the cancer cells (angiogenesis)

Dasatinib, with the above actions, finally disrupts the spread of CML cancer cells.

Administration of Dasakast 50 mg (Dasatinib):
Dasakast (dasatinib) is given in the form of 100 mg dose (2×50 mg tablets) once daily. However, if the condition of patients does not improve, the dose is escalated to 140 mg (2×100 mg tablets) once daily. It can be taken with or without food in the morning or evening. Once swallowed, dasatinib is completely absorbed (bio-available) in 6 hours and is distributed throughout the region of cancer. It is metabolized in liver by different types of proteins and subsequently after completing its action, more than 50% of dasatinib is expelled from the body within 3 to 5 hours.

 

When should Dasakast 50 mg (Dasatinib) be avoided or used cautiously:

• In patients having a severe risk of bleeding (hemorrhage), carry out blood tests regularly
• If patients carry an infection (fever) caused due to decrease in blood cells (myelosuppression)
• If patients have symptoms like swelling, dry cough, shortness of breath or weight gain leading to the loss of fluids (fluid retention) in body
• If patients are suffering from shortness of breath, tiredness, or hypoxia) causing increase in blood pressure (Hypertension)
• If patients had a history of heart problems (heart attack or heart failure)
• If patients are seen with nausea, vomiting, weakness or cramps in the muscles, a condition where the cancerous cells are overkilled spraying their contents in the blood (tumor lysis syndrome), could be present
• If patients are pregnant or planning to get pregnant
• If patients face complications in stomach or intestine

 

Most common side-effects of Dasakast 50 mg (Dasatinib):

• Diarrhoea
• Headache
• Pain in the muscles (myalgia)
• Rashes on the skin
• Nausea
• Tiredness
• Shortness of breath
• Excessive bleeding

 

The uncommon ones are:

• Pain in the stomach and intestinal regions
• Vomiting
• Constipation
• Weight gain
• Chills
• Inconsistent heartbeat (Arrythmia)
• Fever with other signs of infection (Febrile neutropenia)
• Decrease in RBCs i.e. Hemoglobin (anemia)
• Decrease in platelets (thrombocytopenia)

Product Details:

Enzamide (Enzalutamide 40mg) Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.