Amyotrophic Lateral Sclerosis

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Nintedanib  100mg , 150mg is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Nintedanib is safe and effective in children.What are the possible side effects of Nintedanib?
Nintedanib may cause serious side effects, including:
See “What is the most important information I should know about Nintedanib?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Nintedanib.diarrhea, nausea, and vomiting. While you are taking Nintedanib, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Nintedanib may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Nintedanib may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Nintedanib are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.
INDICATIONSIdiopathic Pulmonary FibrosisNintedanib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeNintedanib is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].
Systemic Sclerosis-Associated Interstitial Lung DiseaseNintedanib is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
DOSAGE AND ADMINISTRATIONTesting Prior To Nintedanib AdministrationConduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with Nintedanib [see WARNINGS AND PRECAUTIONS].
Recommended DosageThe recommended dosage of Nintedanib is 150 mg twice daily administered approximately 12 hours apart.
Nintedanib capsules should be taken with food [see CLINICAL PHARMACOLOGY] and swallowed whole with liquid. Nintedanib capsules should not be chewed or crushed because of a bitter taste. The effect of chewing or crushing of the capsule on the pharmacokinetics of nintedanib is not known.

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Hepbest (Tenofovir Alafenamide 25mg)Tablet is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection. Hepbest Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. It is important to keep taking them until your doctor tells you it is safe to stop. Some people may experience headaches as a side effect of this medicine. Please consult your doctor if it persists for a longer duration. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment. Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex. USES OF HEPBEST TABLET HIV infection Chronic hepatitis B virus (HBV) infection BENEFITS OF HEPBEST TABLET In HIV infection Hepbest Tablet is an antiretroviral medicine. It works by preventing HIV from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines. It is not a cure for HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. You must take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people. In Chronic hepatitis B virus (HBV) infection In patients with chronic hepatitis B virus (HBV) infection, Hepbest Tablet works by preventing the HBV virus from multiplying in the body. It helps control the infection and makes the immune system work better. This lowers the chances of getting complications and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines. It is not a cure and should neither be used to prevent HBV infection. You must take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of the medicine. Show Less SIDE EFFECTS OF HEPBEST TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Hepbest Headache HOW TO USE HEPBEST TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepbest Tablet is to be taken empty stomach. HOW HEPBEST TABLET WORKS Hepbest Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

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Myhep All (Sofosbuvir/Velpatasvir 400mg,100mg) Tablet is a combination of two antiviral medicines. This prescription medicine is used in the treatment of chronic hepatitis C virus (HCV) infection. It fights against the viruses to resolve the infection. Myhep All Tablet should be taken in the prescribed dose and duration. It can be taken with or without food, but take it at the same time daily. It is advised not to consume more than the recommended dose. It is important to inform your doctor if you have any health conditions such as liver or kidney disease. It is harmful to consume alcohol along with this medicine, so it is advised to limit or avoid alcohol. The course of the medicine should be completed for better results. The common side effects of this medicine are tiredness and headache. You should drink plenty of fluid and eat a healthy diet to prevent or overcome the side effects. Before taking the medicine, inform your doctor if you are taking any other medicines or supplements. USES OF MYHEP ALL TABLET Treatment of Chronic hepatitis C virus (HCV) infection BENEFITS OF MYHEP ALL TABLET In Treatment of Chronic hepatitis C virus (HCV) infection Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). When the infection moves into a long-lasting stage, it is called chronic hepatitis C virus infection. Myhep All Tablet helps reduce the number of hepatitis C virus by preventing it from spreading in your body. This helps control the infection and helps you recover faster. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. SIDE EFFECTS OF MYHEP ALL TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Myhep All Headache Tiredness HOW TO USE MYHEP ALL TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Myhep All Tablet may be taken with or without food, but it is better to take it at a fixed time. HOW MYHEP ALL TABLET WORKS Myhep All Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time. SAFETY ADVICE warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Myhep All Tablet. Please consult your doctor. warnings Pregnancy SAFE IF PRESCRIBED Myhep All Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breastfeeding SAFE IF PRESCRIBED Myhep All Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving UNSAFE Myhep All Tablet may cause side effects which could affect your ability to drive. Myhep All Tablet, when taken together with other medicines for the treatment of hepatitis c infection, may produce dizziness, blurred vision and this may affect your ability to drive. warnings Kidney CAUTION Myhep All Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Myhep All Tablet may be needed. Please consult your doctor. Limited information is available on the use of Myhep All Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver SAFE IF PRESCRIBED Myhep All Tablet is safe to use in patients with liver disease. No dose adjustment of Myhep All Tablet is recommended. However, inform your doctor if you have any kidney disease as regular monitoring of liver function tests may be advised in some patients while taking this medicine.

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Saxagliptin 5mg Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.
Saxagliptin 5mg 5mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or in combination with other diabetes medicines. It can be taken with or without food.
The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor. Do not stop taking the medicine unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of this medicine include hypoglycemia, upper respiratory tract infection, urinary tract infection, headache, and peripheral edema. It is important to recognize the symptoms of hypoglycemia (such as lightheadedness, sweating, dizziness, fainting, and dry mouth) and know how to deal with it. You can carry sugar or glucose candy and have them to control your symptoms if you experience any. Contact your doctor if any of these side effects do not go away or worry you.
Before taking this medicine, let your doctor know if you have ever had kidney disease, heart disease, or pancreas problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.USES OF Saxagliptin 5mgType 2 diabetes mellitusBENEFITS OF Saxagliptin 5mgIn Type 2 diabetes mellitusSaxagliptin 5mg 5mg Tablet belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It helps increase the amount of insulin your body produces after a meal and to stop your body from releasing too much glucose (sugar) into your blood. This way it lowers the blood glucose levels in your body. It is usually taken once a day and has relatively few common side effects.
Lowering blood glucose levels is an essential part of managing diabetes. Controlling the blood glucose level helps prevent serious complications of diabetes such as kidney damage, blindness, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed for long-term benefits.SIDE EFFECTS OF Saxagliptin 5mgMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Saxagliptin 5mgHypoglycaemia (low blood sugar level) in combination with insulin or sulphonylureaUpper respiratory tract infectionUrinary tract infectionHeadachePeripheral edemaHOW TO USE Saxagliptin 5mgTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Saxagliptin 5mg 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW Saxagliptin 5mg WORKSSaxagliptin 5mg 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

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Geftinat (Gefitinib 250mg) Tablet is used in the treatment of non-small cell lung cancer. It is used in patients in which it has spread to other parts of the body, who have abnormal epidermal growth factor receptor (EGFR) genes, and who have not had previous treatment for cancer.
Geftinat 250mg Tablet can be taken with or without food, but better to have it same time every day for better results. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, rash, vomiting and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.USES OF GEFTINAT TABLETNon-small cell lung cancerBENEFITS OF GEFTINAT TABLETIn Non-small cell lung cancerNon-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Geftinat 250mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.SIDE EFFECTS OF GEFTINAT TABLETMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of GeftinatDiarrheaDry skinLoss of appetiteNauseaRashStomatitis (Inflammation of the mouth)VomitingWeaknessWeight lossHOW TO USE GEFTINAT TABLETTake this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Geftinat 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.HOW GEFTINAT TABLET WORKSGeftinat 250mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.SAFETY ADVICEwarningsAlcoholUNSAFEIt is unsafe to consume alcohol with Geftinat 250mg Tablet.warningsPregnancyCONSULT YOUR DOCTORGeftinat 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.warningsBreastfeedingCONSULT YOUR DOCTORGeftinat 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.warningsDrivingUNSAFEGeftinat 250mg Tablet may cause side effects which could affect your ability to drive.Geftinat 250mg Tablet may make you feel weak. This may affect your driving ability.

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Edaravone is used to help people recover from stroke in Japan, and is used to treat ALS in the US and Japan. It was approved for ALS in the US in 2017 based on a small randomized controlled clinical trial with people who had early-stage ALS in Japan, who were administered the drug for 6 months; it had failed two earlier trials in people with all stages of ALS. It is given by intravenous infusion